| Autor: |
Ryosuke Fujii, Cristian Pattaro, Yoshiki Tsuboi, Yuya Ishihara, Roberto Melotti, Hiroya Yamada, Yoshitaka Ando, Hiroaki Ishikawa, Koji Ohashi, Shuji Hashimoto, Nobuyuki Hamajima, Giulia Barbieri, Dariush Ghasemi-Semeskandeh, Koji Suzuki |
| Rok vydání: |
2023 |
| Předmět: |
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| Zdroj: |
Clinical Biochemistry. 111:54-59 |
| ISSN: |
0009-9120 |
| Popis: |
Previous studies have proposed different formulas of estimating glomerular filtration rate (eGFR) among clinical patients. The comprehensive comparison of eGFR formulas is not well established in a Japanese population. We compared eGFR values and chronic kidney disease (CKD) classification of nine different eGFR in a Japanese general population sample.We analyzed 469 Japanese community-dwelling adults (184 men) without any self-reported kidney disease. GFR estimated using the 4- and 6-parameter Modification of Diet in Renal Disease (MDRD) formulas (MDRD4 and MDRD6); the CKD-EPI formulas based on creatinine with (CKD-EPI-2009) and without race coefficient (CKD-EPI-2021), on cystatin C (CKD-EPI-Cys), on both (CKD-EPI-CreCys); the Japanese creatinine-based formula (JPN-Cre), cystatin C-based formula (JPN-Cys), and modified CKD-EPI formula (JPN-CKD-EPI). CKD stages were defined by KDIGO guidelines (eGFR 60 ml/min/1.73 meGFRJPN-Cre was substantially different from the CKD-EPI formula without race term (CKD-EPI-2021), which means that it is impossible to recalibrate those with a simple coefficient. Although a comparison with measured GFR should be necessary, choice of the estimation method needs caution in clinical decision-making and academic research. |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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