Protein-DNA complexes: specificity and DNA readout mechanisms

Autor:	Shestopalova A. V., Tkachenko M. Yu., Boryskina O. P.
Rok vydání:	2011
Předmět:	mechanisms of direct and indirect readout specificity of protein-nucleic acid interaction protein-nucleic acid complexes QH301-705.5 Genetics Biology (General) QH426-470 General Biochemistry Genetics and Molecular Biology
Zdroj:	Biopolymers and Cell, Vol 27, Iss 1, Pp 3-16 (2011)
ISSN:	1993-6842 0233-7657
DOI:	10.7124/bc.00007c
Popis:	Protein-nucleic acid recognition is essential in a number of cellular processes, in particular, gene regulation, DNA replication and compaction. Studies on the recognition mechanisms show that DNA sequence carries information which is read out by proteins that selectively bind to specific DNA sites. The review is focused on the processes taking place during formation of specific and nonspecific complexes of proteins and DNA. Special attention is paid to direct and indirect mechanisms of sequence-specific recognition. Several examples of protein-nucleic acid complexes are given to illustrate the variety of recognition mechanisms
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1907111f22989d51158750a160ed536d https://doi.org/10.7124/bc.00007c Zobrazit plný text záznamu Plný text ve formátu PDF