Pathophysiology of pulmonary arterial hypertension
| Autor: | Hector O. Ventura, Ben deBoisblanc, Suma Jain |
|---|---|
| Rok vydání: | 2007 |
| Předmět: |
medicine.medical_specialty
Pathology Hypertension Pulmonary 030204 cardiovascular system & hematology 03 medical and health sciences 0302 clinical medicine Smooth muscle Internal medicine Medicine Humans 030212 general & internal medicine business.industry medicine.disease Thrombosis Pulmonary hypertension Pathophysiology Anesthesiology and Pain Medicine medicine.anatomical_structure Pathophysiology of hypertension Cardiology Vascular resistance Etiology medicine.symptom Cardiology and Cardiovascular Medicine business Vasoconstriction |
| Zdroj: | Seminars in cardiothoracic and vascular anesthesia. 11(2) |
| ISSN: | 1089-2532 |
| Popis: | The mechanisms leading to elevations in precapillary pulmonary vascular resistance are complex and likely involve multiple pathways, but the histopathologic sequelae of these processes are restricted to a few findings, primarily neoangiogenesis, intimal and smooth muscle proliferation, vasoconstriction, and/or in situ thrombosis. Regardless of the etiology of pulmonary hypertension, abnormalities in endothelial function are often observed and likely play a central role in mediating structural changes. |
| Databáze: | OpenAIRE |
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