Fish-Rich Diet, Leptin, and Body Mass

Autor: Virend K. Somers, Mikolaj Winnicki, Paolo Pauletto, Massimo Puato, Paolo Palatini, Valentina Accurso, Bradley G. Phillips
Rok vydání: 2002
Předmět:
Zdroj: Circulation. 106:289-291
ISSN: 1524-4539
0009-7322
DOI: 10.1161/01.cir.0000025241.01418.4d
Popis: Background — Leptin has been implicated in cardiovascular disease. A diet rich in fish has been associated with decreased cardiac and vascular risk. Methods and Results — We examined the relationship between diet and leptin in 2 related homogeneous African tribal populations of Tanzania. One tribe consumes freshwater fish as their main diet component (n=279), and the other tribe consumes a primarily vegetarian diet (n=329). In multivariate analysis, plasma leptin levels were associated with type of diet (F=14.3, P P =0.017) and female (5.0±1.9 [fish diet] versus 11.8±1.4 [vegetarian diet] ng/mL, P =0.007) fish eaters had lower plasma leptin levels than did their vegetable diet counterparts, even though body mass index values were virtually identical. Conclusions — A diet rich in fish is associated with lower plasma leptin, independent of body fat. These findings may have implications for understanding the reduced cardiovascular risk in subjects on a high-fish diet.
Databáze: OpenAIRE