Fish-Rich Diet, Leptin, and Body Mass
Autor: | Virend K. Somers, Mikolaj Winnicki, Paolo Pauletto, Massimo Puato, Paolo Palatini, Valentina Accurso, Bradley G. Phillips |
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Rok vydání: | 2002 |
Předmět: |
Leptin
Male medicine.medical_specialty medicine.medical_treatment Fresh Water Vascular risk Tanzania Body Mass Index Cohort Studies Risk Factors Physiology (medical) Internal medicine Animals Humans Medicine Risk factor biology business.industry Diet Vegetarian Insulin Fishes biology.organism_classification Diet Endocrinology Cardiovascular Diseases Homogeneous Freshwater fish Fish Female Cardiology and Cardiovascular Medicine business Body mass index |
Zdroj: | Circulation. 106:289-291 |
ISSN: | 1524-4539 0009-7322 |
DOI: | 10.1161/01.cir.0000025241.01418.4d |
Popis: | Background — Leptin has been implicated in cardiovascular disease. A diet rich in fish has been associated with decreased cardiac and vascular risk. Methods and Results — We examined the relationship between diet and leptin in 2 related homogeneous African tribal populations of Tanzania. One tribe consumes freshwater fish as their main diet component (n=279), and the other tribe consumes a primarily vegetarian diet (n=329). In multivariate analysis, plasma leptin levels were associated with type of diet (F=14.3, P P =0.017) and female (5.0±1.9 [fish diet] versus 11.8±1.4 [vegetarian diet] ng/mL, P =0.007) fish eaters had lower plasma leptin levels than did their vegetable diet counterparts, even though body mass index values were virtually identical. Conclusions — A diet rich in fish is associated with lower plasma leptin, independent of body fat. These findings may have implications for understanding the reduced cardiovascular risk in subjects on a high-fish diet. |
Databáze: | OpenAIRE |
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