Long-term survival and secondary procedures after open or endovascular repair of abdominal aortic aneurysms
| Autor: | Theodorus G. van Schaik, Kak K. Yeung, Hence J. Verhagen, Jorg L. de Bruin, Marc R.H.M. van Sambeek, Ron Balm, Clark J. Zeebregts, Joost A. van Herwaarden, Jan D. Blankensteijn, D.E. Grobbee, J.D. Blankensteijn, A.A.A. Bak, J. Buth, P.M. Pattynama, E.L.G. Verhoeven, A.E. van Voorthuisen, R. Balm, P.W.M. Cuypers, M. Prinssen, M.R.H.M. van Sambeek, A.F. Baas, M.G. Hunink, J.M. van Engelshoven, M.J.H.M. Jacobs, B.A.J.M. de Mol, J.H. van Bockel, J. Reekers, X. Tielbeek, W. Wisselink, N. Boekema, L.M. Heuveling, I. Sikking, J.L. de Bruin, A.V. Tielbeek, J.A. Reekers, P. Pattynama, T. Prins, A.C. van der Ham, J.J.I.M. van der Velden, S.M.M. van Sterkenburg, G.B. ten Haken, C.M.A. Bruijninckx, H. van Overhagen, R.P. Tutein Nolthenius, T.R. Hendriksz, J.A.W. Teijink, H.F. Odink, A.A.E.A. de Smet, D. Vroegindeweij, R.M.M. van Loenhout, M.J. Rutten, J.F. Hamming, L.E.H. Lampmann, M.H.M. Bender, H. Pasmans, A.C. Vahl, C. de Vries, A.J.C. Mackaay, L.M.C. van Dortmont, A.J. van der Vliet, L.J. Schultze Kool, J.H.B. Boomsma, H.R. van Dop, J.C.A. de Mol van Otterloo, T.P.W. de Rooij, T.M. Smits, E.N. Yilmaz, F.G. van den Berg, M.J.T. Visser, E. van der Linden, G.W.H. Schurink, M. de Haan, H.J. Smeets, P. Stabel, F. van Elst, J. Poniewierski, F.E.G. Vermassen |
|---|---|
| Přispěvatelé: | Cardiovascular Biomechanics, Surgery, ACS - Amsterdam Cardiovascular Sciences, Cardiothoracic Surgery, Radiology and Nuclear Medicine, ACS - Atherosclerosis & ischemic syndromes, ACS - Heart failure & arrhythmias, Man, Biomaterials and Microbes (MBM), Vascular Ageing Programme (VAP), Amsterdam Gastroenterology Endocrinology Metabolism, ACS - Microcirculation |
| Jazyk: | angličtina |
| Rok vydání: | 2017 |
| Předmět: |
Male
Time Factors medicine.medical_treatment Vascular damage Radboud Institute for Health Sciences [Radboudumc 16] Postoperative Complications/diagnostic imaging Kaplan-Meier Estimate 030204 cardiovascular system & hematology Endovascular aneurysm repair law.invention Aortic aneurysm 0302 clinical medicine Postoperative Complications Randomized controlled trial Belgium law Risk Factors Cause of Death 030212 general & internal medicine Cause of death Netherlands OUTCOMES Endovascular Procedures II ENDOLEAK Middle Aged RANDOMIZED CONTROLLED-TRIAL Abdominal aortic aneurysm Aortic Aneurysm Intention to Treat Analysis Treatment Outcome Retreatment cardiovascular system Female Cardiology and Cardiovascular Medicine medicine.medical_specialty Abdominal/diagnostic imaging Disease-Free Survival 03 medical and health sciences Blood Vessel Prosthesis Implantation Aneurysm medicine Humans Endovascular Procedures/adverse effects cardiovascular diseases EXPOSURE Blood Vessel Prosthesis Implantation/adverse effects Aged Intention-to-treat analysis business.industry medicine.disease Surgery RADIATION business FOLLOW-UP Abdominal surgery Aortic Aneurysm Abdominal Aortic Aneurysm Abdominal/diagnostic imaging |
| Zdroj: | Journal of Vascular Surgery, 66(5), 1379-1389. Mosby Inc. Journal of Vascular Surgery, 66, 1379-1389 Journal of vascular surgery, 66(5), 1379-1389. Mosby Inc. Journal of Vascular Surgery, 66(5), 1379-1389. MOSBY-ELSEVIER van Schaik, T G, Yeung, K K, Verhagen, H J, de Bruin, J L, van Sambeek, M R H M, Balm, R, Zeebregts, C J, van Herwaarden, J A, Blankensteijn, J D & DREAM trial participants 2017, ' Long-term survival and secondary procedures after open or endovascular repair of abdominal aortic aneurysms ', Journal of Vascular Surgery, vol. 66, no. 5, pp. 1379-1389 . https://doi.org/10.1016/j.jvs.2017.05.122 Journal of Vascular Surgery, 66(5), 1379. Mosby Inc. Journal of Vascular Surgery, 66, 5, pp. 1379-1389 |
| ISSN: | 0741-5214 1379-1389 |
| DOI: | 10.1016/j.jvs.2017.05.122 |
| Popis: | Item does not contain fulltext OBJECTIVE: Randomized trials have shown an initial survival benefit of endovascular over conventional open abdominal aortic aneurysm repair but no long-term difference up to 6 years after repair. Longer follow-up may be required to demonstrate the cumulative negative impact on survival of higher reintervention rates associated with endovascular repair. METHODS: We updated the results of the Dutch Randomized Endovascular Aneurysm Management (DREAM) trial, a multicenter, randomized controlled trial comparing open with endovascular aneurysm repair, up to 15 years of follow-up. Survival and reinterventions were analyzed on an intention-to-treat basis. Causes of death and secondary interventions were compared by use of an events per person-year analysis. RESULTS: There were 178 patients randomized to open and 173 to endovascular repair. Twelve years after randomization, the cumulative overall survival rates were 42.2% for open and 38.5% for endovascular repair, for a difference of 3.7 percentage points (95% confidence interval, -6.7 to 14.1; P = .48). The cumulative rates of freedom from reintervention were 78.9% for open repair and 62.2% for endovascular repair, for a difference of 16.7 percentage points (95% confidence interval, 5.8-27.6; P = .01). No differences were observed in causes of death. Cardiovascular and malignant disease account for the majority of deaths after prolonged follow-up. CONCLUSIONS: During 12 years of follow-up, there was no survival difference between patients who underwent open or endovascular abdominal aortic aneurysm repair, despite a continuously increasing number of reinterventions in the endovascular repair group. Endograft durability and the need for continued endograft surveillance remain key issues. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|