Conserved structural and regulatory regions in the Salmonella typhimurium btuB gene for the outer membrane vitamin B12 transport protein
| Autor: | Robert J. Kadner, C Bradbeer, B.-Y Wei |
|---|---|
| Rok vydání: | 1992 |
| Předmět: |
DNA
Bacterial Salmonella typhimurium Molecular Sequence Data Biological Transport Active In Vitro Techniques Biology medicine.disease_cause Microbiology Gene expression Escherichia coli medicine Molecular Biology Gene Base Sequence Nucleic acid sequence Gene Expression Regulation Bacterial General Medicine Transport protein Vitamin B 12 Biochemistry Genes Bacterial Regulatory sequence Colicin Bacterial outer membrane Bacterial Outer Membrane Proteins Plasmids |
| Zdroj: | Research in Microbiology. 143:459-466 |
| ISSN: | 0923-2508 |
| DOI: | 10.1016/0923-2508(92)90091-2 |
| Popis: | The Salmonella typhimurium btuB gene encodes an outer membrane protein that is necessary for the transport of vitamin B12 and the uptake of the E colicins and bacteriophage BF23. The sequence of this gene showed 87 % identity of the deduced polypeptide to its Escherichia coli homolog, and its product was found to function in transport as effectively in cells of E. coli as did the native protein. The extensive sequence conservation within the first 300 transcribed nucleotides, which include the leader and early part of the coding sequence, supports the proposed role of this region in the regulation of btuB gene expression. |
| Databáze: | OpenAIRE |
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