Lysozyme Activity in Cerebrospinal Fluid
Autor: | Sakari Reitamo, Matti Klockars |
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Rok vydání: | 2009 |
Předmět: |
Male
Pathology medicine.medical_specialty Central nervous system Tuberculous meningitis 03 medical and health sciences chemistry.chemical_compound 0302 clinical medicine Cerebrospinal fluid Diabetic Neuropathies Central Nervous System Diseases Internal Medicine medicine Humans Meningitis In patient 030212 general & internal medicine CSF albumin Aged Aspergillus Epilepsy biology Brain Neoplasms business.industry medicine.disease biology.organism_classification 3. Good health Cerebrovascular Disorders medicine.anatomical_structure chemistry Female Muramidase Differential diagnosis Lysozyme business 030217 neurology & neurosurgery |
Zdroj: | Acta Medica Scandinavica. 199:321-325 |
ISSN: | 0001-6101 |
DOI: | 10.1111/j.0954-6820.1976.tb06739.x |
Popis: | The concentration of lysozyme (LZM) in cerebrospinal fluid (CSF) has been studied in 148 patients to evaluate its possible significance in the differential diagnosis of various diseases affecting the central nervous system (CNS). In the control group only 3 of 45 patients had detectable LZM in their CSF, the highest value being 1.3 mug/ml. The diabetic and epileptic groups did not differ from the control group. Of 8 patients with primary intracranial tumours, 4 had raised CSF-LZM levels. Twenty of 23 uraemic patients had elevated CSF-LZM, the highest value being 3.3 mug/ml. The highest values were found in patients with bacterial meningitis, tuberculous meningitis and leptomeningitis due to Aspergillus. A positive correlation was found between CSF-LZM and protein concentrations. The measurement of LZM may be of value in the diagnosis of inflammatory processes affecting the CNS and in the diagnosis of certain intracranial tumours. |
Databáze: | OpenAIRE |
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