Self-Etching of Metal–Organic Framework Templates during Polydopamine Coating: Nonspherical Polydopamine Capsules and Potential Intracellular Trafficking of Metal Ions
| Autor: | Lu Yang, Pengjiao Zhang, Zihan Ye, Songhai Wu, Zhenkun Zhang, Chunxiong Zheng |
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| Rok vydání: | 2017 |
| Předmět: |
Indoles
Materials science Polymers Metal ions in aqueous solution Capsules Nanotechnology 02 engineering and technology engineering.material 010402 general chemistry 01 natural sciences Metal chemistry.chemical_compound Coating Imidazolate Electrochemistry Humans General Materials Science Chelation Metal-Organic Frameworks Spectroscopy Ions fungi Surfaces and Interfaces 021001 nanoscience & nanotechnology Condensed Matter Physics 0104 chemical sciences Template chemistry Metals visual_art engineering visual_art.visual_art_medium Metal-organic framework 0210 nano-technology Layer (electronics) Nanospheres HeLa Cells |
| Zdroj: | Langmuir. 33:12952-12959 |
| ISSN: | 1520-5827 0743-7463 |
| DOI: | 10.1021/acs.langmuir.7b02811 |
| Popis: | Traditionally, containers made from steel or other metals are not good for making tea, probably due to the fact that polyphenol components in tea can chelate with metal ions. A similar reason might stand behind the observations as reported herein. During the coating of well-defined metal-organic framework (MOF) crystalline particles with polydopamine (PDA) via pH-induced self-polymerization of dopamine, we found that MOF templates automatically etch off during the coating, giving rise to nonspherical PDA capsules that inherit the morphologies of the templates. Such self-etching of MOF templates is ascribed to the chelation of the metal nodes of the MOFs by the catechol moieties in the PDA layer. In addition, the self-etching of the zeolitic imidazolate framework-8 (ZIF-8) with a truncated cubic shape probably follows a crystalline facet-dependent fashion, resulting in intermediate yolk-shell structures with ZIF-8 cargos of various shapes inside a highly biocompatible PDA shell. Incubation of such intermediate hybrid particles with the cancerous HeLa cell line leads to pronounced cytotoxicity, which is tentatively connected with the cellular internalization of the ZIF@PDA nanoparticles because of the cell affinity of the PDA layer. Subsequently, the continuous release of Zn |
| Databáze: | OpenAIRE |
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