Inducing effect of testosterone on the hepatic reduction of zearalenone in the female prepubertal rat

Autor:	Monica Olsen
Rok vydání:	1985
Předmět:	medicine.medical_specialty Androsterone urogenital system Chemistry Uterus Dehydrogenase Toxicology Microbiology chemistry.chemical_compound medicine.anatomical_structure Endocrinology Internal medicine medicine Zearalenone Testosterone Biotechnology
Zdroj:	Mycotoxin Research. 1:51-56
ISSN:	0178-7888
Popis:	The prepubertal responsiveness of 3α-hydroxysteroid dehydrogenase and zeara-lenone-reducing activity to either a large subcutaneous dose of testosterone or dietary zearalenone was investigated in female rats. Testosterone induced both the activity of the 3α-hydroxysteroid dehydrogenase, with androsterone as substrate, and zearalenone reduction to α- and (β-zearalenol. Zearalenone had no effect on the activity of 3α-hydroxysteroid dehydrogenase, but had a slight inducing effect on the zearalenone reduction to β-zearalenol. Both testosterone and zearalenone had a growth-promoting effect on uterus.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::18d0efe4d886a5a0d0fbc2a4838541d6 https://doi.org/10.1007/bf03192003 Zobrazit plný text záznamu Full text from SpringerLink