Neural influences on human esophageal and salivary alkali secretion

Autor: W. D. W. Rees, B. Slee, L. N. Sandle, C. F. Snowdon, C. M. Brown
Rok vydání: 1995
Předmět:
Zdroj: Digestive Diseases and Sciences. 40:1642-1650
ISSN: 1573-2568
0163-2116
DOI: 10.1007/bf02212684
Popis: Esophageal secretion of HCO 3 − ions occurs in opossum and man and may contribute to mucosal defense. Using a perfusion technique, neuroregulatory influences on esophageal and salivary HCO 3 − secretion were investigated in 24 healthy human subjects. The sight and smell of food increased median salivary HCO 3 − output from 424 to 573 μmol/15 min (P=0.014), without significantly altering esophageal HCO 3 − secretion (74–105 μmol/15 min,P=0.24). Atropine reduced both salivary (610 to 68, 17, 10, and 3 μmol/15 min in successive periods;P
Databáze: OpenAIRE