Evaluation of Pregnancy-Related Cells in Endometrial Cytology
| Autor: | Yoshiko Kashimura, Naoyuki Toki, Wakaho Doki, Masamichi Kashimura, Junko Fukuda |
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| Rok vydání: | 2007 |
| Předmět: |
Adult
medicine.medical_specialty Pathology Histology Endometrium Pathology and Forensic Medicine Diagnosis Differential Pregnancy Cytology medicine Atypia Humans Decidual cells Retrospective Studies Partial Hydatidiform Mole Vaginal Smears Gynecology business.industry Anatomical pathology Hydatidiform Mole General Medicine Middle Aged medicine.disease Trophoblasts Abortion Spontaneous medicine.anatomical_structure Uterine Neoplasms Female Placental site nodule Differential diagnosis business |
| Zdroj: | Acta Cytologica. 51:407-411 |
| ISSN: | 1938-2650 0001-5547 |
| DOI: | 10.1159/000325755 |
| Popis: | Objective To determine the significance of pregnancy-related cells in endometrial smears, Study Design Pregnancy-related cells in 4,429 endometrial smear samples were retrospectively analyzed and evaluated for clinicopathologic and cytomorphologic features. Results Of the 4,429 endometrial smears taken for cancer screening, pregnancy-related cells were detected in 12 cases (0.3%). They were estimated cytologically as negative or suspicious and confirmed as cases of spontaneous abortion (8 cases), placental site nodule (3 cases), and partial hydatidiform mole (1 case). Decidual cells were observed in all cases, and some of these showed atypia. Trophoblasts were observed in 5 (41.7%) of the 12 cases. Syncytiotrophoblasts were observed in 1 case (8.3%) and nonsyncytiotrophoblasts in 5 (41.7%) of the 12 cases. Pregnancy-related cells were observed in an endometrial smear in 7 cases; other cases were missed during cytologic examination and were retrospectively identified. Conclusion Pregnancy-related cells are likely to be missed because they are difficult to identify or are surrounded by a cluster of endometrial cells. The decidual cell is a key cell for the cytologic diagnosis of pregnancy-related cells. Determining the existence of pregnancy-related cells in endometrial smears is important for the further assessment of patients and the differential diagnosis of several endometrial lesions. |
| Databáze: | OpenAIRE |
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