Pregnancy-Induced Hypertension, But Not Gestational Diabetes Mellitus, Is a Risk Factor for Venous Thromboembolism in Pregnancy
| Autor: | Hyun Sun Won, Hyun-Ho Shin, Jeong Bae Park, Sung Ja Lee, Moon Seok Yang, Do Yi Kim |
|---|---|
| Rok vydání: | 2011 |
| Předmět: |
Gynecology
medicine.medical_specialty Pregnancy Univariate analysis Obstetrics business.industry Retrospective cohort study Odds ratio equipment and supplies medicine.disease Pulmonary embolism Placenta previa Gestational diabetes Pregnancy-induced hypertension Internal Medicine medicine Original Article cardiovascular diseases Risk factor Cardiology and Cardiovascular Medicine business Venous thromboembolism |
| Zdroj: | Korean Circulation Journal |
| ISSN: | 1738-5520 |
| DOI: | 10.4070/kcj.2011.41.1.23 |
| Popis: | Background and Objectives: The aim of this study was to identify the association of pregnancy-induced hypertension (PIH) or gestational diabetes mellitus (GDM) with the development of venous thromboembolism (VTE). Subjects and Methods: This was a retrospective study of 57,009 pregnancies during 2002-2008 at Cheil General Hospital, Kwandong University. The diagnosis of VTE {deep vein thrombosis or pulmonary embolism (PE)} was based on clot visualization via ultrasound or computed tomography. Results: In total, 27 cases (PE, 20 cases) were detected. The incidence of VTE was 0.47 per 1,000 pregnancies. To determine risk factors associated with pregnancy-induced VTE, univariate analysis using a chi-square test was performed. Cesarean (C)-section, multiple pregnancy, PIH, placenta previa, and assisted reproduction technique (ART) were statistically significant compared to the controls (all, p=0.000). However, age, premature rupture of membrane, and GDM were not statistically related to VTE. Logistic regression analysis was used to calculate the odds ratios for the risk factors. Placenta previa showed a 12.6-fold higher risk, while PIH had a 9.8-fold higher risk for the occurrence of VTE. C-section and ART procedures increased the risk of VTE by 4.2 times compared to that of the controls. Conclusion: Placenta previa and PIH were significant risk factors for VTE, whereas the known traditional risk factors of increased age and GDM were not found to be associated with VTE. (Korean Circ J 2011;41:23-27) |
| Databáze: | OpenAIRE |
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