Purity evaluation of 6 alpha-methylprednisolone acetate by HPLC
| Autor: | E. Ciranni Signoretti, Cavina G, Luisa Valvo, A.L. Savella |
|---|---|
| Rok vydání: | 1993 |
| Předmět: |
Chromatography
Chemistry Clinical Biochemistry Pharmaceutical Science Reversed-phase chromatography Methylprednisolone acetate High-performance liquid chromatography Methylprednisolone Analyse qualitative Analytical Chemistry Qualitative analysis Impurity Drug Discovery Analytical procedures Related impurities Spectroscopy Chromatography High Pressure Liquid |
| Zdroj: | Journal of pharmaceutical and biomedical analysis. 11(7) |
| ISSN: | 0731-7085 |
| Popis: | A high-performance liquid chromatographic method is described for the analysis and identification of related impurities in pharmaceutical-grade 6α-methylprednisolone acetate (MPA). Eight MPA impurities derived from synthesis and/or degradation processes were identified. The method is compared to other analytical procedures recently proposed for the European Pharmacopoeia. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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