Melkersson-Rosenthal syndrome associated with parvovirus b19 viraemia and haemophagocytic lymphohistiocytosis
| Autor: | P. Spaggiari, Sara Balestracci, A. De Maria, F. Tarchino, M. Leva, Giorgio Walter Canonica, Gianni Passalacqua, A. Zolezzi |
|---|---|
| Jazyk: | italština |
| Rok vydání: | 2009 |
| Předmět: |
Male
Pathology medicine.medical_specialty Fatal outcome Viremia Dermatology Severity of Illness Index Lymphohistiocytosis Hemophagocytic Parvoviridae Infections Young Adult Fatal Outcome Melkersson–Rosenthal syndrome Severity of illness Parvovirus B19 Human Humans Medicine Melkersson-Rosenthal Syndrome biology Parvovirus business.industry Parvovirus infection virus diseases biology.organism_classification medicine.disease Immunology business |
| Popis: | We describe a 23-year-old patient who presented acutely with haemophagocytic lymphohistiocytosis (HL) and Melkersson-Rosenthal syndrome (MRS). MRS and HL are two unusual and complex clinical patterns that may present acutely and to our knowledge, an association between them has never been reported. The clinical investigations in this patient led to identification of parvovirus B19 (PB19) viraemia by PCR. Parvovirus infection has been reported as a cause of virus-associated HL, but the presence of PB19 has never been sought or reported as a possible trigger for MRS. This observation suggests a possible association between PB19 and HL, and opens the possibility of its association also with acute-onset MRS. Further investigations for the presence of PB19 in cases of MRS are warranted. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|