Closer location of the tracheoesophageal fistula to the carina in newborns with esophageal atresia and VACTERL association
| Autor: | Henrik Ehrén, Carmen Mesas Burgos, Anders Holmquist, Tina Granholm |
|---|---|
| Rok vydání: | 2019 |
| Předmět: |
Heart Defects
Congenital Male medicine.medical_specialty Fistula Limb Deformities Congenital Anal Canal Tracheoesophageal fistula Kidney 03 medical and health sciences Esophagus 0302 clinical medicine 030225 pediatrics Chart review Bronchoscopy medicine Humans Esophageal Atresia Retrospective Studies business.industry Infant Newborn Disease Management Syndrome General Medicine Perioperative medicine.disease VACTERL association Spine Surgery Trachea Distance measurement 030220 oncology & carcinogenesis Atresia Pediatrics Perinatology and Child Health Etiology Female business Tracheoesophageal Fistula |
| Zdroj: | Journal of Pediatric Surgery. 54:1312-1315 |
| ISSN: | 0022-3468 |
| DOI: | 10.1016/j.jpedsurg.2018.10.062 |
| Popis: | Background VACTERL is a complicated syndrome with an unknown etiology where many studies have failed to identify the cause. In esophageal atresia (EA) roughly 10%–23% also have concurrent anomalies that align with VACTERL disorder. The aim of this study is to investigate if there is a difference regarding localization of the tracheoesophageal fistula between patients with VACTERL and non-VACTERL patients. Methods Retrospective chart review of newborn operated for esophageal atresia between 2006 and 2016 at our Institution was performed. Children with a C-type fistula according to Gross and reliable preoperative tracheoesophageal fistula to carina distance measurement at rigid tracheoscopy were included in the study. Results A total of 90 patients were included in the study. Fifteen of those were diagnosed with VACTERL. Before and after adjusting for weight and gestational week patients with VACTERL had significantly shorter carina to fistula distance at perioperative rigid tracheoscopy (p = Conclusion Patients with VACTERL born with EA type C had shorter carina to fistula distance as shown at perioperative rigid tracheoscopy. The significantly shorter distance may not only present surgical difficulties but may also suggest a structural or molecular difference in the development of the esophageal atresia between the two groups. Level of evidence III. |
| Databáze: | OpenAIRE |
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