Antigen-specific production of immune interferon by T Cells lines
| Autor: | P L Mottram, J. L. Mckimm-Breschkin, Wayne R. Thomas, Jacques F. A. P. Miller |
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| Rok vydání: | 1982 |
| Předmět: |
Interferon type II
Mice Inbred A T-Lymphocytes Immunology Dose-Response Relationship Immunologic Major histocompatibility complex Epitope Cell Line Major Histocompatibility Complex Epitopes Mice Antigen Interferon medicine Animals Immunology and Allergy Mice Inbred BALB C biology Oxazolone Articles In vitro Kinetics Cell culture Mice Inbred CBA biology.protein Interferons Hapten medicine.drug |
| Zdroj: | The Journal of Experimental Medicine |
| ISSN: | 1540-9538 0022-1007 |
| Popis: | Continuous cultures of T cells reactive to the hapten 4-ethoxymethylene-2-phenyloxazolone were tested for interferon production after antigenic stimulation in vitro. Induction of interferon was antigen-specific and also restricted by the I region of the major histocompatibility complex. Kinetics of antigen induced interferon production were different from those reported for mitogen induced synthesis. |
| Databáze: | OpenAIRE |
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