Anesthetic Bladder Capacity is a Clinical Biomarker for Interstitial Cystitis/Bladder Pain Syndrome Subtypes

Autor: Stephen J. Walker, Gopal H. Badlani, Catherine A. Matthews, Carl D. Langefeld, Andre Plair, Robert J. Evans
Rok vydání: 2021
Předmět:
Zdroj: Urology
ISSN: 1527-9995
Popis: OBJECTIVE: To further examine anesthetic bladder capacity as a biomarker for interstitial cystitis/bladder pain syndrome (IC/BPS) patient subtypes, we evaluated demographic and clinical characteristics in a large and heterogeneous female patient cohort. MATERIAL AND METHODS: This is a retrospective review of data from women (n=257) diagnosed with IC/BPS who were undergoing therapeutic bladder hydrodistention (HOD). Assessments included medical history and physical examination, validated questionnaire scores, and anesthetic BC. Linear regression analyses were computed to model the relationship between anesthetic BC and patient demographic data, symptoms, and diagnoses. Variables exhibiting suggestive correlations (p ≤ 0.1) were candidates for a multiple linear regression analysis and were retained if significant (p ≤ 0.05). RESULTS: Multiple regression analysis identified a positive correlation between BC and endometriosis (p=0.028) as well as negative correlations between BC and both ICSI score (p
Databáze: OpenAIRE