Generalized dermatophytosis caused by Trichophyton equinum in 8 juvenile black bears in California
| Autor: | Mark L Anderson, Katherine D. Watson, Dan Famini, Nicholas Shirkey, Brandon Munk, Federico Giannitti, Stella C. McMillin, Deana L. Clifford, Jaime Rudd, Kristin A. Clothier, Leslie W. Woods, Asli Mete |
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| Jazyk: | angličtina |
| Rok vydání: | 2021 |
| Předmět: |
medicine.medical_specialty
dermatophytosis Autopsy Folliculitis medicine.disease_cause Tinea Trichophyton bears medicine Juvenile Animals Exfoliative dermatitis Veterinary Sciences Ursus Skin integumentary system General Veterinary biology Arthrodermataceae biology.organism_classification medicine.disease Dermatology Trichophyton equinum Ursus americanus Dermatophyte Histopathology Zero Hunger Brief Reports medicine.symptom Emaciation Zoology Ursidae |
| Zdroj: | J Vet Diagn Invest Journal of veterinary diagnostic investigation : official publication of the American Association of Veterinary Laboratory Diagnosticians, Inc, vol 34, iss 2 |
| Popis: | From 2014–2019, 8 juvenile black bears ( Ursus americanus) from different geographic regions were presented to the California Department of Fish and Wildlife because of emaciation, alopecia, and exfoliative dermatitis that resulted in death or euthanasia. Autopsy and histopathology revealed that all 8 bears had generalized hyperkeratotic dermatitis, folliculitis, and furunculosis. Skin structures were heavily colonized by fungal hyphae and arthrospores; fungal cultures of skin from 7 bears yielded Trichophyton equinum, a zoophilic dermatophyte reported only rarely in non-equid species. Additional skin conditions included mites (5), ticks (2), and coagulase-negative Staphylococcus sp. infections (2). No other causes of morbidity or mortality were identified. Molecular comparisons performed at the University of Texas Fungal Reference Laboratory determined that all isolates produced identical banding patterns, potentially representing a clonal population. Dermatophytosis is commonly localized and limited to the stratum corneum of the epidermis and hair follicles. Generalized disease with dermal involvement is rare in immunocompetent individuals; illness, malnutrition, age, or immunosuppression may increase susceptibility. Underlying causes for the severe disease impact in these bears were not evident after physical or postmortem examination. The mechanism by which bears from different geographic locations had severe, T. equinum–associated dermatophytosis from a potentially clonal dermatophyte could not be explained and warrants further investigation. |
| Databáze: | OpenAIRE |
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