Supplementary Figure 3 from The Indenoisoquinoline TOP1 Inhibitors Selectively Target Homologous Recombination-Deficient and Schlafen 11-Positive Cancer Cells and Synergize with Olaparib
Autor: | Yves Pommier, Kathleen Kelly, Junko Murai, Moudjib Etemadi, Michael L. Beshiri, Shyam K. Sharan, Zoe Weaver Ohler, Melanie Gordon, Ludmila Szabova, Laetitia Marzi |
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Rok vydání: | 2023 |
DOI: | 10.1158/1078-0432.22471658 |
Popis: | LMP776 is synergistic with talazoparib in BRCA1-/- cells. Cell viability curves of talazoparib in DT40 WT (blue symbols and curves) and BRCA1-/- cells (red) with the indicated concentrations of LMP776. Open symbols and dashed lines correspond to talazoparib alone. |
Databáze: | OpenAIRE |
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