Infertility treatment use in relation to selected adverse birth outcomes
| Autor: | Janet R. Daling, Diana B. Welmerink, Lynda F. Voigt, Beth A. Mueller |
|---|---|
| Rok vydání: | 2009 |
| Předmět: |
Infertility
Adult medicine.medical_specialty Reproductive Techniques Assisted Population Infant Newborn Diseases Congenital Abnormalities Cohort Studies Young Adult Pregnancy medicine Humans education Fetal Death Birth Year education.field_of_study business.industry Obstetrics Infant Newborn Parturition Pregnancy Outcome Obstetrics and Gynecology medicine.disease Placenta previa Obstetric Labor Complications Low birth weight Reproductive Medicine Premature birth Female medicine.symptom business Cohort study |
| Zdroj: | Fertility and sterility. 94(7) |
| ISSN: | 1556-5653 |
| Popis: | To determine whether maternal infertility treatment is associated with adverse outcomes.Population-based cohort study using linked birth certificate-hospital discharge data.Washington State.Live-born singleton infants conceived with infertility treatment between 2003 and 2006 (n = 2,182) and a random sample of live-born singleton infants conceived spontaneously, frequency matched by birth year (n = 10,989).None.Mantel-Haenszel adjusted relative risks (RRs) and 95% confidence intervals (CIs) were computed for low birth weight, delivery at37 weeks, small for gestational age infants, any malformation, placenta previa, and placenta abruptio.Women with infertility treatment were at increased risk of placental abnormalities, including placenta abruptio (RR, 1.6; 95% CI, 1.1-2.5) and placenta previa (RR, 3.0; 95% CI, 2.0-4.7). Their infants were more likely to be delivered at37 weeks (RR, 1.7; 95% CI, 1.4-1.9) or weigh2500 g (RR, 1.4; 95% CI, 1.1-1.7); however, they were not at increased risk of being small for gestational age. An increased risk of malformations was observed in infants born to older women with infertility treatment, but not to younger women.Women using infertility treatment are at increased risk for delivering preterm, placenta previa, and placenta abruptio. Studies with measurement of specific infertility treatments will help identify the mechanisms. |
| Databáze: | OpenAIRE |
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