Persistent severe acute respiratory syndrome coronavirus 2 detection after resolution of coronavirus disease 2019-associated symptoms/signs
| Autor: | Bo young Lee, Seung-Jae Lee, Tae Hyong Kim, Se Yoon Park, Jeong Won Shin, Soon Gyu Yun, Eun Jung Lee, Hyo Ju Son |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2020 |
| Předmět: |
Adult
Male medicine.medical_specialty Saliva viruses Pneumonia Viral Viral Nonstructural Proteins Gastroenterology virus shedding Betacoronavirus Young Adult 03 medical and health sciences 0302 clinical medicine Viral Envelope Proteins Internal medicine medicine Humans SPECIAL COVID-19 Respiratory system Viral shedding Young adult skin and connective tissue diseases Pandemics Retrospective Studies Coronavirus RNA-Dependent RNA Polymerase biology SARS-CoV-2 business.industry fungi virus diseases Retrospective cohort study Middle Aged RNA-Dependent RNA Polymerase biology.organism_classification Reverse transcriptase body regions covid-19 Sputum Medicine Female 030211 gastroenterology & hepatology medicine.symptom Coronavirus Infections business Rapid Communication severe acute respiratory syndrome coronavirus 2 |
| Zdroj: | The Korean Journal of Internal Medicine, Vol 35, Iss 4, Pp 793-796 (2020) The Korean Journal of Internal Medicine |
| ISSN: | 2005-6648 1226-3303 |
| Popis: | There are limited data on the duration of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) RNA in respiratory specimens after resolution of coronavirus disease 2019 (COVID-19)-associated symptoms/signs. We determined duration of SARS-CoV-2 virus shedding in symptomatic patients after remission of symptoms. We investigated the duration of SARS-CoV-2 RNA detection using real-time reverse transcriptase polymerase chain reaction for SARS-CoV-2 in nasopharyngeal/oropharyngeal swabs or sputum or saliva. Six patients were included in the final analysis. The median (range) duration of SARS-CoV-2 viral detection after hospitalization was 34 days (22 to 67). After resolution of symptoms/signs, SARS-CoV-2 RNA was detected for median (range) of 26 days (9 to 48). Among the six patients, one had persistent detection of SARS-CoV-2 RNA until day 67 of hospitalization, which was 30 days after symptom resolution. This case represents the longest duration of SARS-CoV-2 detection, and highlights the need for long-term follow up of COVID-19 patients despite resolution of symptoms to confirm SARS-CoV-2 clearance. |
| Databáze: | OpenAIRE |
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