Accelerated collagen cross-linking in the management of advanced Acanthamoeba keratitis

Autor: López Remigio, Casas del Valle Marco, Traipe Leonidas, Pérez Claudio, Srur Miguel, Kantor Arturo, Raimann Rolf, Cartes Cristian
Jazyk: angličtina
Rok vydání: 2019
Předmět:
Zdroj: Arquivos Brasileiros de Oftalmologia v.82 n.2 2019
Arquivos brasileiros de oftalmologia
Conselho Brasileiro de Oftalmologia (CBO)
instacron:CBO
Arquivos Brasileiros de Oftalmologia, Vol 82, Iss 2, Pp 103-106 (2019)
Popis: Purpose: To report our initial experience in the treatment of Acanthamoeba keratitis with accelerated corneal collagen cross-linking. Methods: Retrospective chart review of patients diagnosed with Acanthamoeba keratitis with progressive corneal melting who were treated with accelerated collagen cross-linking. Results: A total of 6 eyes (5 patients) were reviewed. All the patients received adjuvant therapy with moxifloxacin and chlorhexidine. In 4 cases, the ulcer healed with a mean interval to epithelialization of 108.8 days (range 59-217). In 2 eyes, there was a persistent neurotrophic ulcer. The melting was not progressive in any case, nor did any eye required emergency penetrating keratoplasy. Conclusion: This study suggests a beneficial effect of accelerated collagen cross-linking in cases of Acanthamoeba keratitis with corneal melting. Thus, collagen cross-linking may be considered as adjuvant treatment for Acanthamoeba keratitis.
Databáze: OpenAIRE