Accelerated collagen cross-linking in the management of advanced Acanthamoeba keratitis
Autor: | López Remigio, Casas del Valle Marco, Traipe Leonidas, Pérez Claudio, Srur Miguel, Kantor Arturo, Raimann Rolf, Cartes Cristian |
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Jazyk: | angličtina |
Rok vydání: | 2019 |
Předmět: |
medicine.medical_specialty
Time Factors Riboflavin medicine.medical_treatment Keratitis Cornea Cross-linking reagents lcsh:Ophthalmology Moxifloxacin Ophthalmology medicine Adjuvant therapy Humans Aged Retrospective Studies Aged 80 and over Acanthamoeba keratitis Photosensitizing Agents business.industry Chlorhexidine Reproducibility of Results General Medicine Middle Aged medicine.disease corneal ulcer eye diseases Treatment Outcome medicine.anatomical_structure lcsh:RE1-994 Female Ultraviolet Therapy sense organs Collagen business Adjuvant Follow-Up Studies medicine.drug Corneal ulcer |
Zdroj: | Arquivos Brasileiros de Oftalmologia v.82 n.2 2019 Arquivos brasileiros de oftalmologia Conselho Brasileiro de Oftalmologia (CBO) instacron:CBO Arquivos Brasileiros de Oftalmologia, Vol 82, Iss 2, Pp 103-106 (2019) |
Popis: | Purpose: To report our initial experience in the treatment of Acanthamoeba keratitis with accelerated corneal collagen cross-linking. Methods: Retrospective chart review of patients diagnosed with Acanthamoeba keratitis with progressive corneal melting who were treated with accelerated collagen cross-linking. Results: A total of 6 eyes (5 patients) were reviewed. All the patients received adjuvant therapy with moxifloxacin and chlorhexidine. In 4 cases, the ulcer healed with a mean interval to epithelialization of 108.8 days (range 59-217). In 2 eyes, there was a persistent neurotrophic ulcer. The melting was not progressive in any case, nor did any eye required emergency penetrating keratoplasy. Conclusion: This study suggests a beneficial effect of accelerated collagen cross-linking in cases of Acanthamoeba keratitis with corneal melting. Thus, collagen cross-linking may be considered as adjuvant treatment for Acanthamoeba keratitis. |
Databáze: | OpenAIRE |
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