Diagnostic accuracy of a rapid real-time polymerase chain reaction assay for universal intrapartum group B streptococcus screening
| Autor: | Ludovic Trinquart, Najoua El Helali, Yves Giovangrandi, Aïcha Ly, Jean-Claude Nguyen |
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| Rok vydání: | 2009 |
| Předmět: |
Microbiology (medical)
medicine.medical_specialty Prenatal care Polymerase Chain Reaction Sensitivity and Specificity Group B Streptococcus agalactiae Predictive Value of Tests Pregnancy Streptococcal Infections medicine Rupture of membranes Humans Mass Screening Prospective Studies Antibiotic prophylaxis Pregnancy Complications Infectious Prospective cohort study reproductive and urinary physiology Obstetrics business.industry Infant Newborn Group B Streptococcus Screening bacterial infections and mycoses medicine.disease Surgery Infectious Diseases Predictive value of tests Female France business |
| Zdroj: | Clinical infectious diseases : an official publication of the Infectious Diseases Society of America. 49(3) |
| ISSN: | 1537-6591 |
| Popis: | Background. Intrapartum antibiotic prophylaxis is currently given to mothers who test positive for group B streptococcus (GBS) by antenatal culture-based screening, with a risk-based approach for cases with an unknown GBS status. A rapid real-time polymerase chain reaction (PCR) assay for the detection of GBS became available recently, making intrapartum screening possible. We aimed to assess its diagnostic accuracy and to compare it with antenatal screening. Methods. We conducted a prospective study in a French hospital. All pregnant women giving birth at the maternity ward were considered for inclusion, except those with planned cesarean delivery, with delivery at |
| Databáze: | OpenAIRE |
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