Haemolysis with Bjork-Shiley and Starr-Edwards prosthetic heart valves: a comparative study
| Autor: | M. A. Turner, S. D. Slater, I. A. Sallam, T. D. V. Lawrie, W. H. Bain |
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| Rok vydání: | 1974 |
| Předmět: |
Adult
Male Pulmonary and Respiratory Medicine Aortic valve Anemia Hemolytic medicine.medical_specialty Reticulocytes Time Factors Iron Urinary system medicine.medical_treatment Hemosiderin Hemolysis Prosthesis Hemoglobins Internal medicine medicine Humans Intravascular haemolysis Aged Prosthetic heart L-Lactate Dehydrogenase business.industry Iron levels Significant difference Articles Middle Aged equipment and supplies Haemolysis Blood Cell Count Surgery medicine.anatomical_structure Aortic Valve Heart Valve Prosthesis Cardiology Mitral Valve Female Tricuspid Valve business |
| Zdroj: | Thorax. 29:624-632 |
| ISSN: | 0040-6376 |
| DOI: | 10.1136/thx.29.6.624 |
| Popis: | Slater, S. D., Sallam, I. A., Bain, W. H., Turner, M. A., and Lawrie, T. D. V. (1974). Thorax , 29 , 624-632. Haemolysis with Bjork-Shiley and Starr-Edwards prosthetic heart valves: a comparative study. A comparison was made of the haemolytic complications in 85 patients with two different types of Starr-Edwards cloth-covered ball and cage prosthesis with those in 44 patients with the Bjork-Shiley tilting disc valve. Intravascular haemolysis, as detected by the presence of haemosiderinuria, occurred significantly less often with the Bjork-Shiley than with the Starr-Edwards valve, the overall incidence with aortic, mitral or multiple replacements being 31%, 15%, and 20% for Bjork-Shiley and 94%, 92%, and 88% for Starr-Edwards valves respectively. There was no significant difference in the frequency of haemolysis between each of the two types of Starr-Edwards prosthesis studied at either the aortic (2300 versus 2310 model) or mitral (6300 versus 6310) site. Haemolytic anaemia developed in only one patient with a Bjork-Shiley valve but was common though usually mild with Starr-Edwards prostheses, particularly aortic valve replacements with the 2300 model and in aortic plus mitral (± tricuspid) replacements. The greater severity of haemolysis produced by Starr-Edwards valves, again especially of the latter types, was further demonstrated by higher serum lactate dehydrogenase and 24-hour urinary iron levels. It is concluded that the Bjork-Shiley tilting disc valve represents a significant advance in the amelioration of the haemolytic complications of prosthetic valves. |
| Databáze: | OpenAIRE |
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