Fox Encephalitozoonosis: Isolation of the Agent from an Outbreak in Farmed Blue Foxes (Alopex lagopus) in Finland and Some Hitherto Unreported Pathologic Lesions
Autor: | E. Smeds, K. Nordstoga, Peter Deplazes, J. Åkerstedt, Alexander Mathis |
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Přispěvatelé: | University of Zurich, Akerstedt, J |
Rok vydání: | 2002 |
Předmět: |
Male
10078 Institute of Parasitology Pathology medicine.medical_specialty Antibodies Protozoan Foxes Enzyme-Linked Immunosorbent Assay 610 Medicine & health 2700 General Medicine Disease Outbreaks Serology 600 Technology parasitic diseases medicine Animals Parasite hosting Encephalitozoon cuniculi Finland biology fungi virus diseases Outbreak General Medicine Isolation (microbiology) biology.organism_classification Encephalitozoonosis Congenital infections Fluorescent Antibody Technique Direct Lagopus 570 Life sciences Female |
Zdroj: | Journal of Veterinary Medicine Series B. 49:400-405 |
ISSN: | 1439-0450 0931-1793 |
DOI: | 10.1046/j.1439-0450.2002.00588.x |
Popis: | The farmed blue fox (Alopex lagopus) is particularly susceptible to congenital infections of the microsporidian species Encephalitozoon cuniculi. This report is based on an outbreak of the disease in Finland with high mortality. Five pups (four males and one female) with prolonged disease were examined. The pups had moderate pathological alterations in the kidneys and mild lesions were found in the brains, hearts, salivary and prostatic glands. Diagnosis of E. cuniculi infection was made from serological tests (ELISA, CIA, IFAT), and by in vitro isolation of the parasite from the brain of all five pups investigated. The identity was confirmed by molecular means as E. cuniculi strain II ('mouse strain'). Novel histopathological lesions not described as yet in fox encephalitozoonosis are presented. These include cerebral infarction and necrotizing inflammation of the renal pelvis. The sources and mechanisms of spreading of E. cuniculi to blue foxes are discussed. |
Databáze: | OpenAIRE |
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