Evaluations for surrounding tissue incorporation after implantation of synthetic vascular prostheses in animal models

Autor: Shingo Hirao, Yasue Fujiwara, Tadashi Ikeda, Kenji Minatoya, Hidetoshi Masumoto, Kazuhiro Yamazaki
Rok vydání: 2021
Předmět:
Zdroj: Journal of Artificial Organs. 25:24-33
ISSN: 1619-0904
1434-7229
DOI: 10.1007/s10047-021-01283-3
Popis: Incorporation of surrounding tissues after implantation of synthetic vascular prostheses potentially varies in accordance with implanted prostheses. To evaluate post-implant tissue incorporation, we examined surgical, histological and ultrastructural findings after implantation in animal models. Three types of commercially available prostheses were tested (Gelweave™; Group G, J Graft SHIELD NEO®; Group J and Triplex®; Group T). Prostheses were implanted into Sprague–Dawley rats subcutaneously or sutured on abdominal aorta of Japanese white rabbits. The tissues were surgically examined for adhesion and were subjected to histological evaluations for cellular and tissue infiltration and ultrastructural observations by scanning electron microscopy (SEM). Group G exhibited less tendency in adhesion formation in early phase (rat: G vs J, P
Databáze: OpenAIRE