Agreement on the prescription of antimicrobial drugs
| Autor: | Oscar Fernando Pavão dos Santos, Ana Rita Araújo de Souza, Eduardo Casaroto, Michael B. Edmond, Thiago Zinsly Sampaio Camargo, Elizia Piassi Pedroti, Alexandre Holthausen Campos, Alexandre R. Marra, Carlos Eduardo Saldanha de Almeida, Elivane da Silva Victor |
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| Jazyk: | angličtina |
| Předmět: |
Adult
Male medicine.medical_specialty medicine.drug_class Antibiotics MEDLINE Pharmacology Communicable Diseases Drug Prescriptions Antimicrobial therapy Young Adult Medical microbiology Anti-Infective Agents Physicians medicine Humans Medical prescription Young adult Intensive care medicine Aged Aged 80 and over business.industry Middle Aged Antimicrobial Hospitals Empirical therapy Regimen Infectious Diseases Infectious disease (medical specialty) Female business Research Article |
| Zdroj: | BMC Infectious Diseases |
| ISSN: | 1471-2334 |
| DOI: | 10.1186/s12879-015-0992-y |
| Popis: | Background There is universal awareness of the difficulties faced by doctors when prescribing antimicrobials. Methods Over a six-month period patients hospitalized in the ICU and under treatment with antibiotics and/or antifungals were eligible to participate in the study. The data were assessed by two infectious diseases specialists. Once completed, all case forms were sent independently to both evaluators (TZSC and ARM) by e-mail. Based on the data received, the evaluator completed a form automatically generated on the e-mail and returned it to the original mailbox for further analysis. We assessed the level of agreement between infectious disease specialists and the physicians directly responsible for the decision to begin antimicrobial therapy, as well as to assess the appropriateness of the regimen prescribed. Results Among the antimicrobial regimens prescribed to the 177 patients, 36 % were considered inappropriate by specialist #1 and 38 % were considered inappropriate by specialist #2. We found 78 % agreement by at least one of the infectious disease specialists with the prescribed antimicrobial regimen, and in 49 % of cases both specialists agreed with the prescribed regimen. Both disagreed with the prescribed regimen in 22 % of the cases and they disagreed between themselves in 29 % of the cases. Conclusion This study highlights the difficulties in prescribing effective empirical antimicrobial therapy - they are of such magnitude that even two specialists in infectious diseases, well acquainted with our hospital’s resistance patterns and our patients’ profiles have considerable disagreement. |
| Databáze: | OpenAIRE |
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