| Autor: |
Ryoji Ito, Ikumi Katano, Immanuel W.H. Kwok, Lai Guan Ng, Miyuki Ida-Tanaka, Yusuke Ohno, Yunmei Mu, Hanako Morita, Eiko Nishinaka, Chiyoko Nishime, Misa Mochizuki, Kenji Kawai, Tay Hui Chien, Zhao Yunqian, Fan Yiping, Liew Hui Hua, Teja Celhar, Jerry Kok Yen Chan, Takeshi Takahashi, Motohito Goto, Tomoyuki Ogura, Riichi Takahashi, Mamoru Ito |
| Rok vydání: |
2022 |
| Předmět: |
|
| Zdroj: |
Cell Reports. 41:111841 |
| ISSN: |
2211-1247 |
| Popis: |
Neutrophils are critical mediators during the early stages of innate inflammation in response to bacterial or fungal infections. A human hematopoietic system reconstituted in humanized mice aids in the study of human hematology and immunology. However, the poor development of human neutrophils is a well-known limitation of humanized mice. Here, we generate a human granulocyte colony-stimulating factor (hG-CSF) knockin (KI) NOD/Shi-scid-IL2rg |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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