Indole Alkaloids from Hunteria zeylanica

Autor:	Chun-Xia Zeng, Xiao-Dong Luo, Mei-Fen Bao, Bing-Jie Zhang, Ya-Ping Liu, Ling Ni, Xiang-Hai Cai
Rok vydání:	2017
Předmět:	Insecticides Hunteria zeylanica Stereochemistry Pharmaceutical Science 010402 general chemistry 01 natural sciences Analytical Chemistry Alkaloids Drug Discovery Ic50 values Animals Humans Organic chemistry Nuclear Magnetic Resonance Biomolecular Pharmacology Indole test Aphid Plants Medicinal Molecular Structure biology 010405 organic chemistry Chemistry Organic Chemistry Dihydrocorynantheol biology.organism_classification Antineoplastic Agents Phytogenic Secologanin Tryptamine Alkaloids 0104 chemical sciences Apocynaceae Plant Leaves Rhodobium porosum Complementary and alternative medicine Aphids Molecular Medicine Drug Screening Assays Antitumor Drugs Chinese Herbal HeLa Cells
Zdroj:	Journal of Natural Products. 80:790-797
ISSN:	1520-6025 0163-3864
DOI:	10.1021/acs.jnatprod.5b01035
Popis:	Six new bisindole alkaloids, hunterizeylines A–F (1–6), three new monomers, hunterizeylines G–I (7–9), and 13 known alkaloids were isolated from an aqueous MeOH extract of the twigs and leaves of Hunteria zeylanica. Hunterizeyline H, geissoschizol, and dihydrocorynantheol displayed weak insecticidal activity against the aphid Rhodobium porosum, with IC50 values of 168.2, 360.5, and 290.6 μM, respectively.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::18696f1825c7dc6c9f6462bdaa7ad977 https://doi.org/10.1021/acs.jnatprod.5b01035 Zobrazit plný text záznamu