The burden of chronic obstructive pulmonary disease in the Middle East and North Africa: Results of the BREATHE study
| Autor: | Esra, Uzaslan, Bassam, Mahboub, Majed, Beji, Chakib, Nejjari, Mohamed Awad, Tageldin, Javaid Ahmed, Khan, Salim, Nafti, Nathir M, Obeidat, Abdullah, Sayiner, Siraj, Wali, Nauman, Rashid, Abdelkader, El Hasnaoui |
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| Přispěvatelé: | Ege Üniversitesi, Uludağ Üniversitesi/Tıp Fakültesi/Göğüs Hastalıkları ve Tüberküloz Anabilim Dalı., Uzaslan, Esra, AAI-1004-2021 |
| Jazyk: | angličtina |
| Předmět: |
Male
Daily life activity Pediatrics Work Cardiac & cardiovascular systems Exacerbation Cross-sectional study medicine.medical_treatment United Arab emirates Health care system Parttime employment Comorbidity Sexual intercourse Syrian Arab republic Severity of Illness Index Turkey (republic) Pulmonary Disease Chronic Obstructive Diabetes mellitus Quality of life Africa Northern Cost of Illness Employment status Oxygen therapy Diagnosis Chronic obstructive lung disease Epidemiology Activities of Daily Living Prevalence Coughing Smoking habit Pakistan Social behavior Lebanon Copd assessment test Priority journal Distress syndrome COPD medicine.diagnostic_test Burden of disease Asthma insights Disease burden Middle Aged Cardiovascular disease Adl disability Risk-factors General aspects of disease Hospitalization Morocco Impact Health Resources Egypt Female Emergency care Human Spirometry Adult Pulmonary and Respiratory Medicine medicine.medical_specialty Tunisia Population Saudi Arabia Major clinical study Psychological distress Respiratory system Article Health status Middle East Chronic bronchitis medicine Humans Mortality Disease exacerbation Disease severity Exercise Aged Disability Consultation Jordan Diabetes-mellitus business.industry medicine.disease North Africa Asthma Cardiovascular system & cardiology Dyspnea Cross-Sectional Studies Algeria Quality of Life Work capacity Sleep business Chronic Obstructive Lung Disease Forced Expiratory Volume Stress Psychological |
| Zdroj: | Respiratory Medicine. :S45-S59 |
| ISSN: | 0954-6111 |
| DOI: | 10.1016/S0954-6111(12)70014-8 |
| Popis: | WOS: 000314135500007 PubMed ID: 23290704 COPD is a progressive pulmonary disease which may have a profound impact on general health status and quality of life. This article presents data on the burden of COPD obtained from the BREATHE study in the Middle East, North Africa and Pakistan. This study was a large general population survey of COPD conducted in eleven countries of the region using a standardised methodology. A total of 62,086 subjects were screened, of whom 2,187 fulfilled the "epidemiological" definition of COPD. Data on symptoms, perceived disease severity, impact on work, limitations in activities and psychological distress were collected. 1,392 subjects were analysable of whom 661 (47.5%) reported experiencing an exacerbation of their respiratory condition, 49.4% reported comorbidities and 5.5% reported severe breathlessness as measured with the MRC breathlessness questionnaire. The degree of breathlessness, as well as the perceived severity, was correlated with the overall disease impact as measured with the COPD Assessment Test (p < 0.001). 374 subjects (28.4%) reported that their respiratory condition prevented them from working and this proportion rose to 47.8% in subjects who perceived their respiratory condition as severe. 47.9% of subjects reported difficulties in normal physical exertion, 37.5% in social activities and 31.7% in family activities. Psychological distress was reported by between 42.3% and 53.2% of subjects, depending on the item. In conclusion, the burden of COPD is important, and covers central aspects of daily life. For this reason, physicians should take time to discuss it with their patients, and ensure that the management strategy proposed addresses all their needs. (C) 2012 Elsevier Ltd. All rights reserved. Infomine Research Middle East; MS Health; Nielsen; Omega CRO The BREATHE Study Group would like to thank Selen Atabay and Levent Yildiz for their support throughout the study, Wisco Kajingu (MS Health, Rabat, Morocco) for his contribution to the data analysis, all the participating Contract Research Organisations (Infomine Research Middle East, MS Health, Nielsen and Omega CRO) and finally all GlaxoSmithKline affiliates and personnel involved in the study. |
| Databáze: | OpenAIRE |
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