Working memory systems in the rat
| Autor: | Diana Arman, Jonathon D. Crystal, Alexander Bratch, Alexandra E. Smith, Hannah E. Corbin, Jie-En Wu, Joshua A. Cain, Matthew J. Pizzo, Spencer Kann, Shiloh Cooper, Austin Dunn, Stefan J. Dalecki, Nilda Rivera-Reyes, Amanda R. Doyle |
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| Jazyk: | angličtina |
| Rok vydání: | 2016 |
| Předmět: |
0301 basic medicine
Male Speech recognition Biology Spatial memory General Biochemistry Genetics and Molecular Biology Article Rats Sprague-Dawley 03 medical and health sciences 0302 clinical medicine Encoding (memory) Explicit memory Animals Visual short-term memory Spatial Memory Hardware_MEMORYSTRUCTURES Agricultural and Biological Sciences(all) Biochemistry Genetics and Molecular Biology(all) Working memory Long-term memory Sensory memory Memory rehearsal Rats Smell 030104 developmental biology Memory Short-Term Odorants General Agricultural and Biological Sciences 030217 neurology & neurosurgery |
| Popis: | A fundamental feature of memory in humans is the ability to simultaneously work with multiple types of information using independent memory systems. Working memory is conceptualized as two independent memory systems under executive control [1, 2]. Although there is a long history of using the term "working memory" to describe short-term memory in animals, it is not known whether multiple, independent memory systems exist in nonhumans. Here, we used two established short-term memory approaches to test the hypothesis that spatial and olfactory memory operate as independent working memory resources in the rat. In the olfactory memory task, rats chose a novel odor from a gradually incrementing set of old odors [3]. In the spatial memory task, rats searched for a depleting food source at multiple locations [4]. We presented rats with information to hold in memory in one domain (e.g., olfactory) while adding a memory load in the other domain (e.g., spatial). Control conditions equated the retention interval delay without adding a second memory load. In a further experiment, we used proactive interference [5-7] in the spatial domain to compromise spatial memory and evaluated the impact of adding an olfactory memory load. Olfactory and spatial memory are resistant to interference from the addition of a memory load in the other domain. Our data suggest that olfactory and spatial memory draw on independent working memory systems in the rat. |
| Databáze: | OpenAIRE |
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