An Arylative Ring Expansion Cascade of Fused Cyclobutenes via Short-Lived Intermediates with Planar Chirality

Autor:	Kiyosei Takasu, Yousuke Yamaoka, Norihito Arichi, Ken-ichi Yamada
Rok vydání:	2015
Předmět:	Indoles Molecular Structure Chemistry Stereoisomerism General Chemistry Planar chirality Ring (chemistry) Photochemistry Biochemistry Catalysis Alkadienes Colloid and Surface Chemistry Cyclization Cascade Chirality (chemistry) Cyclobutanes
Zdroj:	Journal of the American Chemical Society. 137:9579-9582
ISSN:	1520-5126 0002-7863
DOI:	10.1021/jacs.5b06576
Popis:	An arylative ring expansion cascade has been developed for the synthesis of medium-sized carbocycles from fused cyclobutenes. This reaction proceeds through a short-lived cis,trans-cycloalkadiene intermediate that is formed by thermal 4π electrocyclic ring opening. Chirality transfer experiments provide direct evidence for the transient generation of the intermediate.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1862d234bf464a7b9d31e5225730f55a https://doi.org/10.1021/jacs.5b06576 Zobrazit plný text záznamu