Two Cells, One Antibody: The Discovery of the Cellular Origins and Transport of Secretory IgA
| Autor: | Charlotte S. Kaetzel, Finn-Eirik Johansen, Jiri Mestecky |
|---|---|
| Rok vydání: | 2017 |
| Předmět: |
0301 basic medicine
biology First line Immunology External secretions chemical and pharmacologic phenomena Specific immunity biochemical phenomena metabolism and nutrition Antibodies Immunoglobulin A Secretory Component 03 medical and health sciences 030104 developmental biology Immune system Immunoglobulin A Secretory biology.protein Humans Immunology and Allergy Secretory IgA Antibody |
| Zdroj: | The Journal of Immunology. 198:1765-1767 |
| ISSN: | 1550-6606 0022-1767 |
| DOI: | 10.4049/jimmunol.1700025 |
| Popis: | Secretory Abs of the IgA and IgM isotypes are the foot soldiers of the mucosal immune system, serving as the first line of specific immunity against inhaled, ingested, and sexually transmitted Ags. Adult humans transport some 3 g/d of secretory (SIgA) into external secretions, more than the daily |
| Databáze: | OpenAIRE |
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