Probiotics and Treatment of Vulvovaginal Candidiasis
| Autor: | malihe farid, mehrnoosh amiri, Leila azizi, somayeh saleki, Maryam Afrakhteh |
|---|---|
| Rok vydání: | 2017 |
| Předmět: |
0301 basic medicine
medicine.medical_specialty Clotrimazole business.industry Probiotics Medical record 030106 microbiology Genital infections Laboratory results Clinical trial Lactobacillus 03 medical and health sciences McNemar's test Medical microbiology Vulvovaginal Candidiasis Internal medicine medicine lcsh:Diseases of the digestive system. Gastroenterology lcsh:RC799-869 business Vaginal candidiasis medicine.drug |
| Zdroj: | International Journal of Enteric Pathogens, Vol 6, Iss 1, Pp 22-26 (2018) |
| ISSN: | 2322-5866 2345-3362 |
| DOI: | 10.15171/ijep.2018.06 |
| Popis: | Background: Genital infections are among the most common diseases for which women refer to gynecologists. Vulvovaginal candidiasis is the second most common infection among women. Objective: A few studies have been conducted on new therapeutic regimens improving the effectiveness of current medications; accordingly, the present study was conducted to compare the effectiveness of clotrimazole with clotrimazole plus probiotics in the treatment of vulvovaginal candidiasis. Materials and Methods: The present double-blind clinical trial was conducted on 80 women admitted to Shohada hospital in Tehran in 2014. The participants were randomly divided into 2 groups of clotrimazole and clotrimazole plus probiotics. The collected data included the participants� sociodemographic information and their medical records along with their symptoms and laboratory results before and after the treatment. Finally, the collected data were analyzed using chi-square test, t test, McNemar test and Fisherexact test. Results: The results showed that both treatments (i.e. clotrimazole and clotrimazole plus probiotics) are equally effective in the treatment of vulvovaginal candidiasis (P = 0.499). Conclusion: The results of the present study indicated that supplementing clotrimazole with probiotics results in similar effects compared to administering clotrimazole alone in the treatment of vulvovaginal candidiasis. |
| Databáze: | OpenAIRE |
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