Injectable platelet-rich fibrin as treatment for temporomandibular joint osteoarthritis: A randomized controlled clinical trial
| Autor: | Isik, Gozde, Kenc, Selin, Koyuncu, Banu Ozveri, Gunbay, Sevtap, Gunbay, Tayfun |
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| Rok vydání: | 2021 |
| Předmět: |
Disorders
Temporomandibular Joint Intraarticular Injection Pain Pain intensity Temporomandibular Joint Disorders Injections Intra-Articular Treatment Outcome Functional jaw movement Otorhinolaryngology Plasma Injection Superior Platelet-Rich Fibrin Injectable platelet -rich fibrin Osteoarthritis Humans Surgery Oral Surgery Range of Motion Articular Plus Hyaluronic-Acid Placebo Reduction Arthrocentesis |
| Zdroj: | Journal of cranio-maxillo-facial surgery : official publication of the European Association for Cranio-Maxillo-Facial Surgery. 50(7) |
| ISSN: | 1878-4119 |
| Popis: | The purpose of this study was to assess the treatment outcomes of intraarticular injection of injectable platelet-rich fibrin (i-PRF) after arthrocentesis in patients with temporomandibular joint osteoarthritis (TMJ-OA). Patients were randomly assigned to one of two treatment groups: those who received intraarticular injection of i-PRF after arthrocentesis procedure -the i-PRF group; and those who un-derwent the arthrocentesis procedure alone -the control group. The primary outcome variable was pain, the level of which was measured preoperatively and at 1, 2, 3, 6, and 12 months postoperatively. The secondary outcome variables included maximum mouth opening (MMO), and lateral and protrusive movements. Of the total of 36 patients, 18 were analyzed in the i-PRF group and 18 in the control group. There were significant differences between the groups in terms of pain levels and measurements of MMO, lateral movement, and protrusive movement over the 12 months of follow-up (p < 0.001). Sig-nificant increases in pain levels and decreases in measurements of MMO, lateral movement, and pro-trusive movement were observed in the control group from the 6th to 12th month postoperatively (p < 0.001). In contrast, no significant differences were found in both pain levels and measurements of MMO, lateral, and protrusive movements for the i-PRF group from the 2nd to the 12th month post-operatively. Within the limitations of the study it seems that intraarticular injection of i-PRF after arthrocentesis should be preferred whenever appropriate because when reducing pain intensity and improving functional jaw movement is the priority. (c) 2022 European Association for Cranio-Maxillo-Facial Surgery. Published by Elsevier Ltd. All rights reserved. Ege University Scientific Research Projects Coordination Unit [22038] This study was supported by the Ege University Scientific Research Projects Coordination Unit (grant number: 22038) . |
| Databáze: | OpenAIRE |
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