Liberation from Dialysis Dependence in a Patient with HIV-Associated Nephropathy (HIVAN) after Combined Antiretroviral Therapy (cART)

Autor:	Virin Rajiv Neil Ramoutar, Raafat Makary, Leighton R. James, Malleswari Ravi, Charles W. Heilig
Jazyk:	angličtina
Rok vydání:	2020
Předmět:	Cart Pediatrics medicine.medical_specialty business.industry medicine.medical_treatment virus diseases Case Report Disease medicine.disease urologic and male genital diseases Antiretroviral therapy Diseases of the genitourinary system. Urology Nephropathy law.invention Progressive renal failure Randomized controlled trial Nephrology law HIV-associated nephropathy Medicine RC870-923 business Dialysis
Zdroj:	Case Reports in Nephrology Case Reports in Nephrology, Vol 2020 (2020)
ISSN:	2090-665X 2090-6641
Popis:	Prior to the advent of combined antiretroviral therapy (cART), human immunodeficiency virus-associated nephropathy (HIVAN) was inevitably associated with rapidly progressive renal failure and dialysis dependence. HIV-1 seropositive patients often met with untimely deaths due to complications of end-stage renal disease (ESRD), opportunistic infections, or other HIV-related end-organ failure. Although the association between cART and improved outcomes in HIVAN has been recognized for over 20 years, no randomized trials have specifically examined this effect to date. In terms of reversal of dialysis-dependent renal failure after cART initiation, only a handful of case reports exist. The authors report a case of a 44-year-old Latino male requiring thrice-weekly haemodialysis in the setting of biopsy-proven HIVAN who was able to stop dialysis in 7 months after being initiated on cART.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::184dacf09667bb9945fd1b54e5ed9a40 http://europepmc.org/articles/PMC7102486 Zobrazit plný text záznamu Plný text ve formátu PDF Plný text ve formátu HTML
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