| Autor: |
Ruiyang Zhao, Julia Velikina, Scott B. Reeder, Shreyas Vasanawala, Michael Jeng, Diego Hernando |
| Rok vydání: |
2022 |
| Předmět: |
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| Zdroj: |
Magnetic resonance in medicineREFERENCES. |
| ISSN: |
1522-2594 |
| Popis: |
To validate QSM-based biomagnetic liver susceptometry (BLS) to measure liver iron overload at 1.5 T and 3.0 T using superconducting quantum interference devices (SQUID)-based BLS as reference.Subjects with known or suspected iron overload were recruited for QSM-BLS at 1.5 T and 3.0 T using eight different protocols. SQUID-BLS was also obtained in each subject to provide susceptibility reference. A recent QSM method based on data-adaptive regularization was used to obtain susceptibility andSusceptibility maps showed high subjective quality for each acquisition protocol across different iron levels. High linear correlation was observed between QSM-BLS and SQUID-BLS at 1.5 T (rThis work evaluated the feasibility and performance of liver QSM-BLS across iron levels and acquisition protocols at 1.5 T and 3.0 T. High correlation and reproducibility were observed between QSM-BLS and SQUID-BLS across protocols and field strengths. In summary, QSM-BLS may enable reliable and reproducible quantification of liver iron concentration. |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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