Long-Term Outcomes of Percutaneous Coronary Intervention for Patients With In-Stent Chronic Total Occlusion Versus De Novo Chronic Total Occlusion
| Autor: | Hong-Bing Li, Yue Wu, Lei Yang, Xiao-Pu Zheng, Wan-Ying Yang, Ke Gao, Li-Hong Fan, Bo-Lin Li, Jie Rong, Zhe Feng, Wei Wu, Miao Zhang, Qi Liang |
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| Rok vydání: | 2021 |
| Předmět: |
Male
medicine.medical_specialty Time Factors medicine.medical_treatment 030204 cardiovascular system & hematology Coronary Angiography Revascularization Risk Assessment Coronary Restenosis Angina Lesion 03 medical and health sciences Percutaneous Coronary Intervention 0302 clinical medicine Risk Factors Surveys and Questionnaires Internal medicine medicine Humans cardiovascular diseases 030212 general & internal medicine Aged business.industry Percutaneous coronary intervention Stent Middle Aged medicine.disease Treatment Outcome Coronary Occlusion Chronic Disease Propensity score matching Conventional PCI Cardiology Female Stents medicine.symptom Cardiology and Cardiovascular Medicine business Mace |
| Zdroj: | Angiology. 72:740-748 |
| ISSN: | 1940-1574 0003-3197 |
| DOI: | 10.1177/0003319721998575 |
| Popis: | Limited data are available on long-term outcomes and health status in the treatment of in-stent coronary chronic total occlusion (IS-CTO) and de novo coronary chronic total occlusion (de novo CTO). This study compared the long-term clinical outcomes and health status of percutaneous coronary intervention (PCI) for patients with IS-CTO versus patients with de novo CTO in the drug-eluting stent era. We screened 483 consecutive patients with 1 CTO lesion, including 81 patients with IS-CTO and 402 patients with de novo CTO. Propensity score matching was used to balance baseline characteristics between the 2 groups. The clinical end point was major adverse cardiac events (MACE). The success rates of CTO lesion revascularization were similar in both groups. In the propensity score-matched patients, after a median follow-up of 36 months, MACE was observed in 32.8% of patients with IS-CTO versus 13.5% of the patients with de novo CTO ( P < .001), mainly driven by target-vessel revascularization (21.9% vs 6.7%; P < .01). Moreover, patients with IS-CTO had significantly worse Seattle Angina Questionnaire anginal stability scores than the patients with de novo CTO. In conclusion, patients with IS-CTO after PCI had a worse clinical outcome, mainly MACE, and a poorer anginal stability in the long term than patients with de novo CTO. |
| Databáze: | OpenAIRE |
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