Safety and Efficacy of Radiofrequency Ablation of Common Atrial Flutter in Elderly Patients:. A Single Center Prospective Study
Autor: | Naïma Zarqane-Sliman, Cécile Romeyer-Bouchard, Marc Messier, Régis Gonthier, Abdel Khiel, Antoine Da Costa, Bernard Samuel, Karl Isaaz |
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Rok vydání: | 2003 |
Předmět: |
Adult
Male medicine.medical_specialty Radiofrequency ablation medicine.medical_treatment Catheter ablation Single Center law.invention Recurrence Risk Factors law Internal medicine medicine Humans Prospective Studies Prospective cohort study Aged Aged 80 and over Analysis of Variance Ejection fraction business.industry Atrial fibrillation General Medicine Middle Aged medicine.disease Treatment Outcome Atrial Flutter Catheter Ablation Cardiology Female Electrophysiologic Techniques Cardiac Cardiology and Cardiovascular Medicine Complication business Atrial flutter Follow-Up Studies |
Zdroj: | Pacing and Clinical Electrophysiology. 26:1729-1734 |
ISSN: | 1540-8159 0147-8389 |
Popis: | Little data is available concerning the invasive treatment of atrial flutter (AFL) in elderly patients. The purpose of this prospective study was to evaluate the risks, safety, and follow-up of radiofrequency (RF) catheter ablation of common AFL in patients >75 years old (n = 61) (Group I) compared to patients younger than 75 years (n = 187) (Group II). The study population consisted of 248 patients (81% men/19% women), 21 to 96 years old (mean 66.3 +/- 12 years) with AFL, referred for RF from June 1999 to June 2001. RF endpoint was the assessment of the bidirectional block. The cumulative risk of atrial fibrillation (AF) was analyzed by the Kaplan-Meier method and log-rank test. The mean follow-up was 12.4 +/- 9 months. No complication occurred. Group I (80.1 +/- 4.5 years) did not differ significantly from Group II (61 +/- 11 years) regarding: AF history before ablation (34.4% vs 39.8%), structural heart disease (54% vs 42%), LVEF (57%+/- 12% vs 58%+/- 12%), left atrial size (43.8 +/- 7 vs 42.5 +/- 7), cava-tricuspid isthmus dimension (40 +/- 10 vs 39 +/- 4 mm), bidirectional block (100% vs 96.2%), RF application (12.5 +/- 10 vs 13.5 +/- 12 minutes), AFL recurrence (3.3% vs 5.3%), antiarrhythmic agents at hospital discharge (34.4% vs 38.9%), mean follow-up (12 +/- 9 vs 13 +/- 9 months) and AF occurrence (29.5% vs 20.3%; P = 0.2). Of these, the incidence of AF in patients without prior history (n = 150) was 7 (18%) of 39 for Group I and 11 (10%) of 111 for Group II (P = 0.1) after follow-up. Catheter ablation of AFL in very elderly patients appears to be a reasonable approach regarding feasibility, effectiveness, and low procedural risk. |
Databáze: | OpenAIRE |
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