Exfoliative cheilitis (EC) in AIDS: association with Candida infection
| Autor: | Peter A. Reichart, Andrea Maria Schmidt-Westhausen, D. Weigel, H. D. Pohle |
|---|---|
| Rok vydání: | 1997 |
| Předmět: |
Adult
Male Cancer Research medicine.medical_specialty Saliva Pathology Antifungal Agents Epithelium Pathology and Forensic Medicine Candidiasis Oral HIV Seronegativity Immunopathology Candida albicans Humans Medicine Vermilion border Sida Fluconazole Mycosis Candida AIDS-Related Opportunistic Infections biology business.industry Middle Aged biology.organism_classification medicine.disease Dermatology Lip CD4 Lymphocyte Count stomatognathic diseases medicine.anatomical_structure Cheilitis Otorhinolaryngology Periodontics Female Viral disease Oral Surgery business medicine.drug |
| Zdroj: | Journal of Oral Pathology and Medicine. 26:290-293 |
| ISSN: | 1600-0714 0904-2512 |
| DOI: | 10.1111/j.1600-0714.1997.tb01239.x |
| Popis: | Forty-seven of 165 patients with AIDS (28.5%) showed exfoliative cheilitis (EC), predominantly of the lower lip (n = 37). Histologically, hyphae were revealed in 23 of 47 cases (49%). In 14 of 23 specimens the histological and microbiological findings were in accordance. Smears of the vermilion border revealed Candida albicans in half of the cases (51%); however, combinations with C. krusei, C. tropicalis and C. glabrata were also seen. Twenty of 35 patients given fluconazole either prophylactically or therapeutically showed clinical signs of oral candidiasis. Frequent moistening of the lips may result in infection of the vermilion border with Candida species; consequent desiccation of the lips will lead to scale formation and exfoliation. Smears of the vermilion border of the lower lip of 20 controls with AIDS were positive in four cases. Twenty HIV-negative controls without EC showed negative microbiological results for Candida species. Exfoliative cheilitis may be associated with Candida infection in some cases and may be considered another variant of candidiasis in AIDS patients. |
| Databáze: | OpenAIRE |
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