The case of undiagnosed immunodeficiency in child from mother with leukemia anamnesis
| Autor: | Natalia Hyryavenko, Mykola Serhiiovych Lyndin, Iryna Vitaliivna Tarasova, Alla Yurchenko, O. I. Smiyan, Anatolii Mykolaiovych Romaniuk, Vladyslav Volodymyrovych Sikora, Artem Mykhailovych Piddubnyi, Oksana Kostiantynivna Romaniuk, Kateryna Sikora, Anna Borysivna Korobchanska |
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| Rok vydání: | 2018 |
| Předmět: |
імунодефіцит
0301 basic medicine Pediatrics medicine.medical_specialty вакцинація Case Report гострий лімфобластний лейкоз acute lymphoblastic leukemia імунна система Miscarriage 03 medical and health sciences тимус 0302 clinical medicine Immune system thymus hemic and lymphatic diseases medicine иммунодефицит Immunodeficiency вакцинация Anamnesis селезінка business.industry острый лимфобластный лейкоз fungi food and beverages hemic and immune systems General Medicine vaccination medicine.disease селезенка Vaccination иммунная система immune system Leukemia 030104 developmental biology Premature birth 030220 oncology & carcinogenesis Gestation spleen business immunodeficiency |
| Zdroj: | Interventional Medicine & Applied Science |
| ISSN: | 2061-5094 2061-1617 |
| Popis: | Acute lymphoblastic leukemia (ALL) in pregnant women is rare experience, but it can complicate the gestation by increasing the risk of miscarriage and premature birth. However, the adequate carrying of the pregnancy is possible for women who suffered from leukemia in childhood and achieved the remission during the treatment. Furthermore, there are some facts about the possibility of immunosuppression in children whose parents suffer from various immunodeficiency disorders, including ALL. This clinical case demonstrates the importance of correct diagnostics in order to reveal the congenital pathologies of the immune system in children, whose parents suffered from lymphocytic leukemia, even in case of full clinical and laboratory remission for a significant period of time. In the hospital, the thread metric approach was used for sepsis diagnostics. Conducted treatment was ineffective due to the inadequate immune response in the child and lack of the targeted adjusted measures to immunodeficiency disorder. The present case demonstrates the congenital T-cells immunodeficiency in a child who was complicated by the development of acute ulceronecrotic enterocolitis after vaccination. The treatment that was targeted mainly at the agent eradication did not give the desired results due to non-responsiveness of the immune system of the child. |
| Databáze: | OpenAIRE |
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