Direct and rapid electrochemical immunosensing system based on a conducting polymer
| Autor: | Q.D. Zhang, Benoît Piro, Huynh Thien Duc, S. Reisberg, Vincent Noël, L.A. Dang, Minh-Chau Pham |
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| Rok vydání: | 2010 |
| Předmět: |
Serum
chemistry.chemical_classification Conductive polymer Time Factors Chromatography Polymers Chemistry Nanotechnology Context (language use) Biosensing Techniques Polymer Reference Standards Conjugated system Enzymes Immobilized Electrochemistry Signal Analytical Chemistry Copolymer Sulfhydryl Compounds Biosensor Acetic Acid Naphthoquinones |
| Zdroj: | Talanta. 82:608-612 |
| ISSN: | 0039-9140 |
| Popis: | A system device using multifunctional conjugated copolymer poly(5-hydroxy-1,4-naphthoquinone-co-hydroxy-2-thioacetic acid-1,4-naphthoquinone) acting both as immobilizing and transducing element for reagentless immunosensor has been constructed. Its functionality was evaluated in an antigen-antibody interaction model using ovalbumin-anti-ovalbumin. It was shown that the system specifically detects via electrochemical signal the antigen-antibody immune interaction in a reagentless context. Comparison to the conventional ELISA technique relevant to performance and sensitivity was presented. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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