Predictor of Early Administration of Antibiotics and a Volume Resuscitation for Young Infants with Septic Shock
| Autor: | Hiroshi Sakakibara, Yuho Horikoshi, Nobuaki Inoue, Osamu Nomura, Yoshihiko Morikawa, Takateru Ihara |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2021 |
| Předmět: |
Microbiology (medical)
Tachycardia medicine.medical_specialty Resuscitation RM1-950 Logistic regression tachycardia Biochemistry Microbiology Article Sepsis sepsis Internal medicine Heart rate medicine Pharmacology (medical) General Pharmacology Toxicology and Pharmaceutics business.industry Septic shock infants Odds ratio medicine.disease 1-h bundle Confidence interval Infectious Diseases Therapeutics. Pharmacology medicine.symptom business |
| Zdroj: | Antibiotics, Vol 10, Iss 1414, p 1414 (2021) Antibiotics Volume 10 Issue 11 |
| ISSN: | 2079-6382 |
| Popis: | (1) Background: It is critical to administer antibiotics and fluid bolus within 1 h of recognizing sepsis in pediatric patients. This study aimed to identify the predictor of the successful completion of a 1-h sepsis bundle for infants with suspected sepsis. (2) Methods: This is an observational study using a prospective registry including febrile young infants (aged < 90 days) who visited a pediatric emergency department with a core body temperature of 38.0 °C or higher and 36.0 °C or lower. Univariate and logistic regression analyses were conducted to determine the predictor (s) of successful sepsis bundle completion. (3) Results: Of the 323 registered patients, 118 patients with suspected sepsis were analyzed, and 38 patients (32.2%) received a bundle-compliant treatment. Among potential variables, such as age, sex, and vital sign parameters, the logistic regression analysis showed that heart rate (odds ratio: OR 1.02 95% confidence interval: 1.00–1.04) is a significant predictor of the completion of a 1-h sepsis bundle. (4) Conclusions: We found that tachycardia facilitated the sepsis recognition and promoted the successful completion of a 1-h sepsis bundle for young infants with suspected septic shock and a possible indicator for improving the quality of the team-based sepsis management. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|