Deep Cutaneous Neoscytalidium dimidiatum Infection: Successful Outcome with Amphotericin B Therapy
| Autor: | Pei-Lun Sun, Chau-Yee Ng, Ting-Shu Wu, Po-Yen Huang, Yen-Mu Wu, Shih-Jyun Yang |
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| Rok vydání: | 2018 |
| Předmět: |
Male
Microbiological Techniques 0301 basic medicine medicine.medical_specialty Antifungal Agents Itraconazole Veterinary (miscellaneous) 030106 microbiology Applied Microbiology and Biotechnology Microbiology 030207 dermatology & venereal diseases 03 medical and health sciences 0302 clinical medicine Medical microbiology Pharmacotherapy Ascomycota Amphotericin B DNA Ribosomal Spacer medicine Dermatomycoses Humans DNA Fungal Abscess Aged 80 and over Voriconazole Foot business.industry Cellulitis Sequence Analysis DNA Middle Aged medicine.disease Dermatology Phaeohyphomycosis Treatment Outcome Molecular Diagnostic Techniques Female business Agronomy and Crop Science medicine.drug |
| Zdroj: | Mycopathologia. 184:169-176 |
| ISSN: | 1573-0832 0301-486X |
| DOI: | 10.1007/s11046-018-0308-z |
| Popis: | Phaeohyphomycosis is a term used to describe a heterogenous group of cutaneous and systemic mycotic infections caused by melanized fungi. Many fungi have been reported as pathogens of this disease. The disease spectrum ranges from superficial cutaneous infections, deep cutaneous infections, to systemic infections with internal organ involvement. We report two cases of deep cutaneous phaeohyphomycosis on the foot clinically presenting as cellulitis with abscess formation. The pathogens were isolated from the lesion and both were identified as Neoscytalidium dimidiatum by their colony morphology, microscopic features, and sequences of internal transcribed spacers of ribosomal DNA. Both patients did not respond to the therapy with voriconazole and itraconazole, but improved after intravenous amphotericin B. |
| Databáze: | OpenAIRE |
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