Cutaneous Angiolymphoid Hyperplasia in a Dog
| Autor: | Rei Nakahira, M. Kato, Masaki Michishita, Kimimasa Takahashi, Satoshi Soeta, Rina Furumoto, Y. Katori, Toshiyuki Ishiwata, H. Sasaki, R.D. Obara, Hisashi Yoshimura |
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| Rok vydání: | 2017 |
| Předmět: |
Male
CD31 Pathology medicine.medical_specialty Endothelium CD3 Vimentin Pathology and Forensic Medicine 030207 dermatology & venereal diseases 03 medical and health sciences Dogs 0302 clinical medicine Antigen medicine Animals Dog Diseases Angiolymphoid hyperplasia with eosinophilia General Veterinary biology Germinal center Angiolymphoid Hyperplasia with Eosinophilia Hyperplasia medicine.disease medicine.anatomical_structure 030220 oncology & carcinogenesis biology.protein |
| Zdroj: | Journal of Comparative Pathology. 157:57-60 |
| ISSN: | 0021-9975 |
| DOI: | 10.1016/j.jcpa.2017.05.004 |
| Popis: | Summary A 5-year-old male miniature dachshund was presented with a dermal nodule on the left forelimb that increased to 5 mm in diameter over a 2-month period. Grossly, the nodule was firm, and both the external and cut surfaces were homogeneously pale pink in colour. Microscopically, the nodule was comprised of mainly plump endothelial cells and inflammatory cells; among the latter, lymphocytes were predominant, with few scattered plasma cells, mast cells and macrophages. Lymphoid follicles with germinal centres were often observed. Mitotic figures were not observed amongst the endothelial cells. Immunohistochemically, the endothelial cells were positive for vimentin, factor VIII-related antigen and CD31, and the surrounding cells were positive for smooth muscle actin. Lymphocytes expressed CD3 or BLA36. These findings led to a diagnosis of cutaneous angiolymphoid hyperplasia. To the best of our knowledge, this is the first report of a cutaneous proliferative disorder comprising an admixture of proliferating vascular endothelial cells and lymphocytic infiltration with follicle formation in a dog. |
| Databáze: | OpenAIRE |
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