Mechanical mitral valve replacement: a multicenter study of outcomes with use of 15-to 17-mm prostheses
| Autor: | Felix Haas, Ryan E. Accord, Mark G. Hazekamp, Gerald R. Marx, Wouter J. van Leeuwen, Herbert van Wetten, Angelika Muter, Rinske IJsselhof, Martijn G. Slieker, Paul H. Schoof, Meena Nathan, Kimberlee Gauvreau |
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| Přispěvatelé: | Cardiothoracic Surgery |
| Jazyk: | angličtina |
| Rok vydání: | 2020 |
| Předmět: |
Male
Reoperation Pulmonary and Respiratory Medicine medicine.medical_specialty medicine.medical_treatment Heart Valve Diseases INFANTS CHILDREN 030204 cardiovascular system & hematology Prosthesis Design Prosthesis RECOMMENDATIONS 03 medical and health sciences 0302 clinical medicine Aortic valve repair All institutes and research themes of the Radboud University Medical Center Mechanical Mitral Valve Aortic valve replacement Mitral valve MELODY medicine Humans Adverse effect PREDICTORS Netherlands Retrospective Studies Heart Valve Prosthesis Implantation RISK business.industry Other Research Radboud Institute for Health Sciences [Radboudumc 0] Mitral valve replacement Infant Retrospective cohort study medicine.disease United States EVOLUTION Surgery Survival Rate Treatment Outcome medicine.anatomical_structure 030228 respiratory system Heart Valve Prosthesis Mitral Valve Female Cardiology and Cardiovascular Medicine business |
| Zdroj: | The Annals of Thoracic Surgery, 110(6), 2062-2069. ELSEVIER SCIENCE INC Annals of Thoracic Surgery, 110, 6, pp. 2062-2069 Annals of Thoracic Surgery, 110(6), 2062-2069. Elsevier Inc. Annals of thoracic surgery, 110(6), 2062-2069. ELSEVIER SCIENCE INC Annals of Thoracic Surgery, 110, 2062-2069 |
| ISSN: | 0003-4975 |
| Popis: | Background. The aim of this study was to evaluate early and mid-term outcomes (mortality and prosthetic valve reintervention) after mitral valve replacement with 15- to 17-mm mechanical prostheses.Methods. A multicenter, retrospective cohort study was performed among patients who underwent mitral valve replacement with a 15- to 17-mm mechanical prosthesis at 6 congenital cardiac centers: 5 in The Netherlands and 1 in the United States. Baseline, operative, and follow-up data were evaluated.Results. Mitral valve replacement was performed in 61 infants (15 mm, n = 17 [28%]; 16 mm, n = 18 [29%]; 17 mm, n = 26 [43%]), of whom 27 (47%) were admitted to the intensive care unit before surgery and 22 (39%) required ventilator support. Median age at surgery was 5.9 months (interquartile range [IQR] 3.2-17.4), and median weight was 5.7 kg (IQR, 4.5-8.8). There were 13 in-hospital deaths (21%) and 8 late deaths (17%, among 48 hospital survivors). Major adverse events occurred in 34 (56%). Median follow-up was 4.0 years (IQR, 0.4-12.5) First prosthetic valve replacement (n = 27 [44%]) occurred at a median of 3.7 years (IQR, 1.9-6.8). Prosthetic valve endocarditis was not reported, and there was no mortality related to prosthesis replacement. Other reinterventions included permanent pacemaker implantation (n = 9 [15%]), subaortic stenosis resection (n = 4 [7%]), aortic valve repair (n = 3 [5%], and aortic valve replacement (n = 6 [10%]).Conclusions. Mitral valve replacement with 15- to 17-mm mechanical prostheses is an important alternative to save critically ill neonates and infants in whom the mitral valve cannot be repaired. Prosthesis replacement for outgrowth can be carried out with low risk. (C) 2020 by The Society of Thoracic Surgeons. Published by Elsevier Inc. |
| Databáze: | OpenAIRE |
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