Higher level of faecal SCFA in women correlates with metabolic syndrome risk factors
| Autor: | Sylvia do Carmo Castro Franceschini, Célia Ferreira, Josefina Bressan, Maria do Carmo Gouveia Peluzio, Łukasz Grześkowiak, Tatiana Fiche Salles Teixeira |
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| Rok vydání: | 2012 |
| Předmět: |
Adult
Blood Glucose medicine.medical_specialty medicine.medical_treatment Medicine (miscellaneous) Blood Pressure Carbohydrate metabolism ta3111 Body Mass Index chemistry.chemical_compound Feces Insulin resistance Risk Factors Internal medicine Medicine Humans Insulin Obesity Adiposity Metabolic Syndrome Nutrition and Dietetics business.industry Cholesterol Cholesterol HDL medicine.disease Fatty Acids Volatile Diet Endocrinology Blood pressure chemistry Body Composition Female Metabolic syndrome Insulin Resistance Waist Circumference business Energy Intake Body mass index |
| Zdroj: | The British journal of nutrition. 109(5) |
| ISSN: | 1475-2662 |
| Popis: | SCFA provide energy to the host and influence lipid and glucose metabolism, suggesting that they may have an impact on the occurrence of metabolic risk factors. The aim of the present study was to determine the concentration of SCFA in faeces of lean and obese individuals and to analyse whether associations between faecal SCFA and metabolic syndrome parameters are present. Lean (n20) and obese (n20) women of similar age (28·5 (sd7·6)v.30·7 (sd6·5) years,P= 0·33) participated in the study. Anthropometric measurements, body composition, blood pressure and biochemical parameters were assessed. SCFA were extracted from faeces and quantified by GC. Blood pressure and blood glucose, although within the normal limits, were higher in the obese group compared to lean subjects (PPv.0·044,P= 0·024), propionic (0·021v.0·051,P= 0·007) and acetic (0·03v.0·061,P= 0·01). SCFA correlated positively with metabolic syndrome risk factors such as adiposity, waist circumference and HOMA index (PP |
| Databáze: | OpenAIRE |
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