Combinatorial and rational approaches to polymer synthesis for medicine☆

Autor:	Daniel G. Anderson, Kerry Peter Mahon, Michael S. Goldberg
Rok vydání:	2008
Předmět:	Tissue Engineering Combinatorial Chemistry Techniques Polymers Chemistry Drug discovery Stem Cells Rational design Pharmaceutical Science Combinatorial biology Nanotechnology Article Drug Delivery Systems Pharmaceutical technology Drug Design Nucleic Acids Drug delivery Humans
Zdroj:	Advanced Drug Delivery Reviews. 60:971-978
ISSN:	0169-409X
DOI:	10.1016/j.addr.2008.02.005
Popis:	High-throughput, combinatorial methods have revolutionized small molecule synthesis and drug discovery. By combining automation, miniaturization, and parallel synthesis techniques, large collections of new compounds have been synthesized and screened. It is becoming increasingly clear that these same approaches can also assist the discovery and development of novel biomaterials for medicine. This review examines combinatorial and rational polymer synthesis for medical applications, including stem cell engineering and nucleic acid drug delivery.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::181e39ca4a6b6d5056fad39e15ba08d5 https://doi.org/10.1016/j.addr.2008.02.005 Zobrazit plný text záznamu Full Text from ScienceDirect