Altered Cellular Distribution of Hexokinase in Skeletal Muscle after Exercise
| Autor: | J. L. Durstine, D. M. Meyers, D. R. Van Houten, J. M. Davis |
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| Rok vydání: | 1992 |
| Předmět: |
Male
medicine.medical_specialty Physical Exertion Physical Therapy Sports Therapy and Rehabilitation Physical exercise Mitochondrion Biology chemistry.chemical_compound Gastrocnemius muscle Hexokinase Internal medicine Organelle medicine Animals Orthopedics and Sports Medicine Fatigue chemistry.chemical_classification Muscles Skeletal muscle Rats Inbred Strains Mitochondria Muscle Rats medicine.anatomical_structure Endocrinology Enzyme chemistry Cellular distribution |
| Zdroj: | International Journal of Sports Medicine. 13:436-438 |
| ISSN: | 1439-3964 0172-4622 |
| DOI: | 10.1055/s-2007-1021294 |
| Popis: | The purpose of this study was to determine the effects of a single period of swim exercise to exhaustion on the cellular distribution of hexokinase in rat skeletal muscle. The gastrocnemius muscle from male rats exercised (n = 16) to exhaustion or allowed to remain inactive (n = 14) was analyzed for hexokinase activity (HK) in the whole muscle homogenate and the mitochondrial-rich fraction. Although exercise produced a slight, non-significant, increase in HK activity in the whole muscle homogenate (p less than 0.09), HK activity in the mitochondrial-rich fraction was significantly increased in the exercised muscle (p less than 0.02). This shift in the cellular distribution of HK is towards the more active mitochondrial bound form and indicates an enhanced regulation of HK activity during physical exercise. |
| Databáze: | OpenAIRE |
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