Supplementary Figure 9B from Somatic Epigenetic Silencing of RIPK3 Inactivates Necroptosis and Contributes to Chemoresistance in Malignant Mesothelioma

Autor: Joseph R. Testa, Siddharth Balachandran, Raja M. Flores, Suresh C. Jhanwar, Suresh Ramanathan, Eric A. Ross, Lauren A. Fox, Vladimir Khazak, Ting Zhang, Anna-Mariya Kukuyan, Craig W. Menges, Suraj Peri, Mitchell Cheung, Eleonora Sementino, Yinfei Tan
Rok vydání: 2023
DOI: 10.1158/1078-0432.22473972
Popis: Drug sensitivity differences between 12 RIPK3-negative and 3 RIPK3-positive human MM cell lines as assessed by MTS assay. Treatment of MM cell lines with three different doses of doxorubicin. First three bars in each bar graph represent viability of RIPK3-positive (+) MM cell lines, M49, M29 and M217, respectively. The bars shown to the right in each graph represent the viability of each of the 12 RIPK3-negative (-) MM lines. All drug treatments were for 72 h.
Databáze: OpenAIRE